NF-kB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression

The interleukin (IL)-1 family cytokines are regulated on transcriptional and posttranscriptional levels. Pattern recognition and cytokine receptors control pro-IL-1β transcription while inflammasomes regulate the proteolytic processing of pro-IL-1β. The NLRP3 inflammasome, however, assembles in resp...

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Detalhes bibliográficos
Main Authors: Bauernfeind, Franz, Horvath, Gabor, Stutz, Andrea, Alnemri, Emad S., MacDonald, Kelly, Speert, David, Fernandes-Alnemri, Teresa, Wu, Jianghong, Monks, Brian G., Fitzgerald, Katherine A., Hornung, Veit, Latz, Eicke
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824855/
https://ncbi.nlm.nih.gov/pubmed/19570822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901363
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