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Reactive oxygen species inhibitors block priming, but not activation of the NLRP3 inflammasome

A common denominator among the multiple damage-inducing agents that ultimately lead to the activation of NLRP3 has not yet been identified. Recently, the production of reactive oxygen species (ROS) has been suggested to act as a common event upstream of the NLRP3 inflammasome machinery. Since de nov...

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Detalhes bibliográficos
Main Authors: Bauernfeind, Franz, Bartok, Eva, Rieger, Anna, Franchi, Luigi, Núñez, Gabriel, Hornung, Veit
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131480/
https://ncbi.nlm.nih.gov/pubmed/21677136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100613
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