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Reactive oxygen species inhibitors block priming, but not activation of the NLRP3 inflammasome
A common denominator among the multiple damage-inducing agents that ultimately lead to the activation of NLRP3 has not yet been identified. Recently, the production of reactive oxygen species (ROS) has been suggested to act as a common event upstream of the NLRP3 inflammasome machinery. Since de nov...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131480/ https://ncbi.nlm.nih.gov/pubmed/21677136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100613 |
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