Autoinhibition of Acetylcholine Binding to Torpedo Electroplax; A Possible Molecular Mechanism for Desensitization

Binding of [(3)H]acetylcholine (measured by equilibrium dialysis) to a particulate preparation of Torpedo electroplax exhibits autoinhibition at concentrations higher than 1 μM. It is suggested that autoinhibition results from acetylcholine binding to regulatory sites on its receptor macromolecules....

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Proc Natl Acad Sci U S A
Päätekijät:	Eldefrawi, M. E., O'Brien, R. D.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	National Academy of Sciences 1971
Aiheet:	Biological Sciences: Biochemistry
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389336/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4332243/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.9.2006
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