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Autoinhibition of Acetylcholine Binding to Torpedo Electroplax; A Possible Molecular Mechanism for Desensitization

Binding of [(3)H]acetylcholine (measured by equilibrium dialysis) to a particulate preparation of Torpedo electroplax exhibits autoinhibition at concentrations higher than 1 μM. It is suggested that autoinhibition results from acetylcholine binding to regulatory sites on its receptor macromolecules....

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Bibliografische gegevens
Hoofdauteurs: Eldefrawi, M. E., O'Brien, R. D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1971
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC389336/
https://ncbi.nlm.nih.gov/pubmed/4332243
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