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Novel Adamantyl Arotinoids that Inhibit IκB Kinase-α and IκB Kinase-β
A series of analogs of the adamantyl arotinoid (AdAr) chalcone 5 (MX781) having halogenated benzyloxy substituents at C2′ and heterocyclic derivatives replacing the chalcone group were found to inhibit IκBα kinase α (IKKα) and IκBα kinase β (IKKβ) activities. The growth inhibitory activity of some a...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3892996/ https://ncbi.nlm.nih.gov/pubmed/23653373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201300100 |
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