Estradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2-deficient LAM cells

Lymphangioleiomyomatosis (LAM) is a progressive neoplastic disorder that leads to lung destruction and respiratory failure primarily in women. LAM is typically caused by tuberous sclerosis complex 2 (TSC2) mutations resulting in mTORC1 activation in proliferative smooth muscle–like cells in the lung...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Li, Chenggang, Lee, Po-Shun, Sun, Yang, Gu, Xiaoxiao, Zhang, Erik, Guo, Yanan, Wu, Chin-Lee, Auricchio, Neil, Priolo, Carmen, Li, Jing, Csibi, Alfredo, Parkhitko, Andrey, Morrison, Tasha, Planaguma, Anna, Kazani, Shamsah, Israel, Elliot, Xu, Kai-Feng, Henske, Elizabeth Petri, Blenis, John, Levy, Bruce D., Kwiatkowski, David, Yu, Jane J.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892971/
https://ncbi.nlm.nih.gov/pubmed/24395886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131080
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars