TSC2 regulates microRNA biogenesis via mTORC1 and GSK3β

Tuberous sclerosis complex (TSC) is an autosomal dominant disease caused by germline inactivating mutations of TSC1 or TSC2. In TSC-associated tumors of the brain, heart, skin, kidney and lung, inactivation of both alleles of TSC1 or TSC2 leads to hyperactivation of the mTORC1 pathway. The TSC/mTORC...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Hum Mol Genet
Autors principals: Ogórek, Barbara, Lam, Hilaire C, Khabibullin, Damir, Liu, Heng-Jia, Nijmeh, Julie, Triboulet, Robinson, Kwiatkowski, David J, Gregory, Richard I, Henske, Elizabeth P
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5905583/
https://ncbi.nlm.nih.gov/pubmed/29509898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy073
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars