Prion Transmission Prevented by Modifying the β2-α2 Loop Structure of Host PrP(C)

Zoonotic prion transmission was reported after the bovine spongiform encephalopathy (BSE) epidemic, when >200 cases of prion disease in humans were diagnosed as variant Creutzfeldt-Jakob disease. Assessing the risk of cross-species prion transmission remains challenging. We and others have studie...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Kurt, Timothy D., Bett, Cyrus, Fernández-Borges, Natalia, Joshi-Barr, Shivanjali, Hornemann, Simone, Rülicke, Thomas, Castilla, Joaquín, Wüthrich, Kurt, Aguzzi, Adriano, Sigurdson, Christina J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2014
Ämnen:
Brief Communications
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891945/
https://ncbi.nlm.nih.gov/pubmed/24431459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4636-13.2014
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