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Alloimmune response results in expansion of autoreactive donor CD4(+) T cells in transplants that can mediate chronic GVHD

Chronic graft versus host disease (cGVHD) is considered an autoimmune-like disease mediated by donor CD4(+) T cells, but the origin of the autoreactive T cells is still controversial. Here, we report that transplantation of DBA/2 donor spleen cells into thymectomized MHC-matched allogeneic BALB/c re...

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Bibliografische gegevens
Hoofdauteurs: Zhao, Dongchang, Young, James S., Chen, Yu-Hong, Shen, Elizabeth, Yi, Tangsheng, Todorov, Ivan, Chu, Peiguo G., Forman, Stephen J., Zeng, Defu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891909/
https://ncbi.nlm.nih.gov/pubmed/21149609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002195
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