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Alloimmune response results in expansion of autoreactive donor CD4(+) T cells in transplants that can mediate chronic GVHD
Chronic graft versus host disease (cGVHD) is considered an autoimmune-like disease mediated by donor CD4(+) T cells, but the origin of the autoreactive T cells is still controversial. Here, we report that transplantation of DBA/2 donor spleen cells into thymectomized MHC-matched allogeneic BALB/c re...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3891909/ https://ncbi.nlm.nih.gov/pubmed/21149609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002195 |
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