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Building blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosis

The central role of the Bcl-2 family in regulating apoptotic cell death was first identified in the 1980s. Since then, significant in-roads have been made in identifying the multiple members of this family, characterizing their form and function and understanding how their interactions determine whe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Westphal, D, Kluck, R M, Dewson, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890949/
https://ncbi.nlm.nih.gov/pubmed/24162660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.139
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