β-Catenin induces T-cell transformation by promoting genomic instability

Deregulated activation of β-catenin in cancer has been correlated with genomic instability. During thymocyte development, β-catenin activates transcription in partnership with T-cell–specific transcription factor 1 (Tcf-1). We previously reported that targeted activation of β-catenin in thymocytes (...

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Xehetasun bibliografikoak
Egile Nagusiak: Dose, Marei, Emmanuel, Akinola Olumide, Chaumeil, Julie, Zhang, Jiangwen, Sun, Tianjiao, Germar, Kristine, Aghajani, Katayoun, Davis, Elizabeth M., Keerthivasan, Shilpa, Bredemeyer, Andrea L., Sleckman, Barry P., Rosen, Steven T., Skok, Jane A., Le Beau, Michelle M., Georgopoulos, Katia, Gounari, Fotini
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2014
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890837/
https://ncbi.nlm.nih.gov/pubmed/24371308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315752111
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