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Wnt/β-catenin signaling in T-cells drives epigenetic imprinting of pro-inflammatory properties and promotes colitis and colon cancer

The density and type of lymphocytes that infiltrate colon tumors are predictive of the clinical outcome of colon cancer. High densities of TH17 cells and inflammation predict poor outcome, while infiltration by Tregs that naturally suppress inflammation is associated with longer patient survival. Ho...

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מידע ביבליוגרפי
Main Authors: Keerthivasan, Shilpa, Aghajani, Katayoun, Dose, Marei, Molinero, Luciana, Khan, Mohammad W., Venkatesvaran, Vysak, Weber, Christopher, Emmanuel, Akinola Olumide, Sun, Tianjao, Ramos, Elena M., Keshavarzian, Ali, Mulcahy, Mary, Blatner, Nichole, Khazaie, Khashayarsha, Gounari, Fotini
פורמט: Artigo
שפה:Inglês
יצא לאור: 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020714/
https://ncbi.nlm.nih.gov/pubmed/24574339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3007607
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