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β-Catenin/Tcf Determines the Outcome of Thymic Selection in Response to αβTCR Signaling()
Thymic maturation of T cells depends on the intracellular interpretation of αβTCR signals by processes that are poorly understood. In this study, we report that α-catenin/Tcf signaling was activated in double-positive thymocytes in response to TCR engagement and impacted thymocyte selection. TCR eng...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4695211/ https://ncbi.nlm.nih.gov/pubmed/19717519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901369 |
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