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Current status of IL-10 and regulatory T-cells in cancer
PURPOSE OF REVIEW: Tumor growth elicits antigen-specific cytotoxic as well as immune suppressive responses. Interleukin-10 (IL-10) is a key immune-suppressive cytokine produced by regulatory T-cells (Tregs) and by helper T-cells (TH). Here we review pleiotropic functions of IL-10 that impact the imm...
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| Publicado no: | Curr Opin Oncol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4322764/ https://ncbi.nlm.nih.gov/pubmed/24076584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0000000000000006 |
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