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Mast cells promote small bowel cancer in a tumor stage-specific and cytokine-dependent manner

Mast cells (MCs) are tissue resident sentinels that mature and orchestrate inflammation in response to infection and allergy. While they are also frequently observed in tumors, the contribution of MCs to carcinogenesis remains unclear. Here, we show that sequential oncogenic events in gut epithelia...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Saadalla, Abdulrahman M., Osman, Abu, Gurish, Michael F., Dennis, Kristen L., Blatner, Nichole R., Pezeshki, Abdulmohammad, McNagny, Kelly M., Cheroutre, Hilde, Gounari, Fotini, Khazaie, Khashayarsha
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5816178/
https://ncbi.nlm.nih.gov/pubmed/29429965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716804115
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