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Intrathymic proliferation wave essential for Vα14(+) natural killer T cell development depends on c-Myc
The molecular requirements for invariant Vα14-bearing natural killer T cells (iNKT) in the thymus are poorly understood. A minute population of ≈500 newly selected CD69(+)CD24(+) stage 0 (ST0) iNKT cells gives rise to ≈100 times more CD44(neg/lo)CD24(−) stage 1 (ST1) cells, which then generate simil...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2689024/ https://ncbi.nlm.nih.gov/pubmed/19423665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812255106 |
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