Elevated cysteine-rich protein 61 (CCN1) promotes skin aging via upregulation of IL-1β in chronically sun-exposed human skin

Chronic exposure of human skin to solar ultraviolet (UV) irradiation causes premature skin aging, which is characterized by reduced type I collagen production and increased fragmentation of the dermal collagenous extracellular matrix. This imbalance of collagen homeostasis is mediated, in part, by e...

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Bibliographic Details
Main Authors: Qin, Zhaoping, Okubo, Toru, Voorhees, John J., Fisher, Gary J., Quan, Taihao
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889915/
https://ncbi.nlm.nih.gov/pubmed/23881607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-013-9565-4
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