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Oxidant Exposure Induces Cysteine-Rich Protein 61 (CCN1) via c-Jun/AP-1 to Reduce Collagen Expression in Human Dermal Fibroblasts

Human skin is a primary target of oxidative stress from reactive oxygen species (ROS) generated from both extrinsic and intrinsic sources. Oxidative stress inhibits the production of collagen, the most abundant protein in skin, and thus contributes to connective tissue aging. Here we report that cys...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Qin, Zhaoping, Robichaud, Patrick, He, Tianyuan, Fisher, Gary J., Voorhees, John J., Quan, Taihao
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275215/
https://ncbi.nlm.nih.gov/pubmed/25536346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115402
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