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Retinoids Suppress Cysteine-rich Protein 61 (CCN1), a Negative Regulator of Collagen Homeostasis, in Skin Equivalent Cultures and Aged Human Skin in vivo

Alterations of connective tissue collagen are prominent features of both chronologically aged and photoaged (aging due to sun exposure) human skin. These age-related abnormalities are mediated in part by CCN family member, CCN1 (cysteine-rich protein 61). CCN1 is elevated in the dermis of both chron...

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Autors principals: Quan, Taihao, Qin, Zhaoping, Shao, Yuan, Xu, Yiru, Voorhees, John J., Fisher, Gary J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120908/
https://ncbi.nlm.nih.gov/pubmed/21488975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0625.2011.01278.x
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