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REDUCED EXPRESSION OF CONNECTIVE TISSUE GROWTH FACTOR (CTGF/CCN2), MEDIATES COLLAGEN LOSS IN CHRONOLOGICALLY-AGED HUMAN SKIN
Reduced production of type I procollagen is a prominent feature of chronologically-aged human skin. Connective tissue growth factor (CTGF/CCN2), a downstream target of the transforming growth factor-β (TGF-β)/Smad pathway, is highly expressed in numerous fibrotic disorders, where it is believed to s...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2877594/ https://ncbi.nlm.nih.gov/pubmed/19641518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2009.224 |
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