Solar Ultraviolet Irradiation Reduces Collagen in Photoaged Human Skin by Blocking Transforming Growth Factor-β Type II Receptor/Smad Signaling

Ultraviolet (UV) irradiation from the sun reduces production of type I procollagen (COLI), the major structural protein in human skin. This reduction is a key feature of the pathophysiology of premature skin aging (photoaging). Photoaging is the most common form of skin damage and is associated with...

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Hauptverfasser: Quan, Taihao, He, Tianyuan, Kang, Sewon, Voorhees, John J., Fisher, Gary J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2004
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618600/
https://ncbi.nlm.nih.gov/pubmed/15331399
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