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Ultraviolet irradiation represses TGF-β type II receptor transcription through a 38 base pair sequence in the proximal promoter in human skin fibroblasts

Transforming growth factor-β (TGF-β) is a major regulator of collagen gene expression in human skin fibroblasts. Cellular responses to TGF-β are mediated primarily through its cell surface type I (TβRI) and type II (TβRII) receptors. Ultraviolet (UV) irradiation impairs TGF-β signaling largely due t...

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Bibliografski detalji
Glavni autori: He, Tianyuan, Quan, Taihao, Fisher, Gary J.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176812/
https://ncbi.nlm.nih.gov/pubmed/25234828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/exd.12389
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