Structural Basis for Carbapenemase Activity of the OXA-23 β-Lactamase from Acinetobacter baumannii

Dissemination of Acinetobacter baumannii strains harboring class D β-lactamases producing resistance to carbapenem antibiotics severely limits our ability to treat deadly Acinetobacter infections. Susceptibility determination in the A. baumannii background and kinetic studies with a homogeneous prep...

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Autors principals: Smith, Clyde A., Antunes, Nuno Tiago, Stewart, Nichole K., Toth, Marta, Kumarasiri, Malika, Chang, Mayland, Mobashery, Shahriar, Vakulenko, Sergei B.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888872/
https://ncbi.nlm.nih.gov/pubmed/24012371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2013.07.015
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