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Structure of the extended-spectrum class C β-lactamase ADC-1 from Acinetobacter baumannii

ADC-type class C β-lactamases comprise a large group of enzymes that are encoded by genes located on the chromosome of Acinetobacter baumannii, a causative agent of serious bacterial infections. Overexpression of these enzymes renders A. baumannii resistant to various β-lactam antibiotics and thus s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bhattacharya, Monolekha, Toth, Marta, Antunes, Nuno Tiago, Smith, Clyde A., Vakulenko, Sergei B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949520/
https://ncbi.nlm.nih.gov/pubmed/24598745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004713033014
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