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Class D β-lactamases do exist in Gram-positive bacteria

Production of β-lactamases of the four molecular classes (A, B, C, and D) is the major mechanism of bacterial resistance to β-lactams, the largest class of antibiotics that have saved countless lives since their inception 70 years ago. Although several hundred efficient class D enzymes have been ide...

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Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Toth, Marta, Antunes, Nuno Tiago, Stewart, Nichole K., Frase, Hilary, Bhattacharya, Monolekha, Smith, Clyde, Vakulenko, Sergei
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684797/
https://ncbi.nlm.nih.gov/pubmed/26551395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1950
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