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The Class A β-Lactamase FTU-1 Is Native to Francisella tularensis

The class A β-lactamase FTU-1 produces resistance to penicillins and ceftazidime but not to any other β-lactam antibiotics tested. FTU-1 hydrolyzes penicillin antibiotics with catalytic efficiencies of 10(5) to 10(6) M(−1) s(−1) and cephalosporins and carbapenems with catalytic efficiencies of 10(2)...

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Detalhes bibliográficos
Main Authors: Antunes, Nuno T., Frase, Hilary, Toth, Marta, Vakulenko, Sergei B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264220/
https://ncbi.nlm.nih.gov/pubmed/22083489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05305-11
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