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Structural Basis for Progression Toward the Carbapenemase Activity in the GES Family of β-Lactamases
Carbapenem antibiotics have become therapeutics of last resort for treatment of difficult infections. Emergence of class A β-lactamases that have the ability to inactivate carbapenems in the past few years is a disconcerting clinical development, in light of the diminished options for treatment of i...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610538/ https://ncbi.nlm.nih.gov/pubmed/23148776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja308197j |
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