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Gene Silencing by Gold Nanoshell-Mediated Delivery and Laser-Triggered Release of Antisense Oligonucleotide and siRNA

The approach of RNA interference (RNAi)- using antisense DNA or RNA oligonucleotides to silence activity of a specific pathogenic gene transcript and reduce expression of the encoded protein- is very useful in dissecting genetic function and holds significant promise as a molecular therapeutic. A ma...

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Detalhes bibliográficos
Main Authors: Huschka, Ryan, Barhoumi, Aoune, Liu, Qing, Roth, Jack A., Ji, Lin, Halas, Naomi J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888232/
https://ncbi.nlm.nih.gov/pubmed/22862291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn301135w
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