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Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides

The potential use of antisense and siRNA oligonucleotides as therapeutic agents has elicited a great deal of interest. However, a major issue for oligonucleotide-based therapeutics involves effective intracellular delivery of the active molecules. In this Survey and Summary, we review recent reports...

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Bibliographic Details
Main Authors: Juliano, Rudy, Alam, Md. Rowshon, Dixit, Vidula, Kang, Hyumin
Format: Artigo
Language:Inglês
Published: Oxford University Press 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475625/
https://ncbi.nlm.nih.gov/pubmed/18558618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn342
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