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Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides
The potential use of antisense and siRNA oligonucleotides as therapeutic agents has elicited a great deal of interest. However, a major issue for oligonucleotide-based therapeutics involves effective intracellular delivery of the active molecules. In this Survey and Summary, we review recent reports...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2475625/ https://ncbi.nlm.nih.gov/pubmed/18558618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn342 |
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