Polymersome delivery of siRNA and antisense oligonucleotides

siRNA and antisense oligonucleotides, AON, have similar size and negative charge and are often packaged for in vitro delivery with cationic lipids or polymers–but exposed positive charge is problematic in vivo. Here we demonstrate loading and functional delivery of RNAi and AON with non-ionic, nano-...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kim, Younghoon, Tewari, Manorama, Pajerowski, J. David, Cai, Shenshen, Sen, Shamik, Williams, Jason, Sirsi, Shashank, Lutz, Gordon, Discher, Dennis E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740336/
https://ncbi.nlm.nih.gov/pubmed/19084037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2008.10.020
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