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Polymersome delivery of siRNA and antisense oligonucleotides
siRNA and antisense oligonucleotides, AON, have similar size and negative charge and are often packaged for in vitro delivery with cationic lipids or polymers–but exposed positive charge is problematic in vivo. Here we demonstrate loading and functional delivery of RNAi and AON with non-ionic, nano-...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2740336/ https://ncbi.nlm.nih.gov/pubmed/19084037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2008.10.020 |
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