Polymersome delivery of siRNA and antisense oligonucleotides

siRNA and antisense oligonucleotides, AON, have similar size and negative charge and are often packaged for in vitro delivery with cationic lipids or polymers–but exposed positive charge is problematic in vivo. Here we demonstrate loading and functional delivery of RNAi and AON with non-ionic, nano-...

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書誌詳細
主要な著者: Kim, Younghoon, Tewari, Manorama, Pajerowski, J. David, Cai, Shenshen, Sen, Shamik, Williams, Jason, Sirsi, Shashank, Lutz, Gordon, Discher, Dennis E.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740336/
https://ncbi.nlm.nih.gov/pubmed/19084037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2008.10.020
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