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Biological Barriers to Therapy with Antisense and siRNA Oligonucleotides

Attaining the full therapeutic utility of antisense and siRNA oligonucleotides will require understanding of the biological barriers that stand between initial administration of these drugs and their final actions within cells. This article examines some of the key barriers that affect the biodistri...

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Detalhes bibliográficos
Main Authors: Juliano, R, Bauman, J, Kang, H, Ming, X
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758224/
https://ncbi.nlm.nih.gov/pubmed/19397332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900093r
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