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Gene silencing by siRNAs and antisense oligonucleotides in the laboratory and the clinic

Synthetic nucleic acids are commonly used laboratory tools for modulating gene expression and have the potential to be widely used in the clinic. Progress towards nucleic acid drugs, however, has been slow and many challenges remain to be overcome before their full impact on patient care can be unde...

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Detalhes bibliográficos
Main Authors: Watts, Jonathan K., Corey, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916955/
https://ncbi.nlm.nih.gov/pubmed/22069063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2993
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