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Chemistry, mechanism and clinical status of antisense oligonucleotides and duplex RNAs
RNA plays a central role in the expression of all genes. Because any sequence within RNA can be recognized by complementary base pairing, synthetic oligonucleotides and oligonucleotide mimics offer a general strategy for controlling processes that affect disease. The two primary antisense approaches...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5829639/ https://ncbi.nlm.nih.gov/pubmed/29240946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1239 |
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