pVHL-Mediated Transcriptional Repression of c-Myc by Recruitment of Histone Deacetylases

The biological functions of Myc are to regulate cell growth, apoptosis, cell differentiation and stem-cell self-renewal. Abnormal accumulation of c-Myc is able to induce excessive proliferation of normal cells. von Hippel-Lindau protein (pVHL) is a key regulator of hypoxia-inducible factor1α (HIF1α)...

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Bibliographische Detailangaben
Hauptverfasser: Hwang, In-Young, Roe, Jae-Seok, Seol, Ja-Hwan, Kim, Hwa-Ryeon, Cho, Eun-Jung, Youn, Hong-Duk
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korea Society for Molecular and Cellular Biology 2012
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887712/
https://ncbi.nlm.nih.gov/pubmed/22286234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-012-2268-3
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