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Recruitment of histone deacetylase 4 by transcription factors represses interleukin-5 transcription

The critical role of IL-5 (interleukin-5) in eosinophilic inflammation implicates it as a therapeutic target for allergic diseases. The aim of the present study was to elucidate the molecular basis for the involvement of reversible histone acetylation in IL-5 transcriptional regulation. We provide e...

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Bibliografiske detaljer
Main Authors: Han, Songyan, Lu, Jun, Zhang, Yu, Cheng, Cao, Han, Liping, Wang, Xiuli, Li, Lin, Liu, Chunyan, Huang, Baiqu
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698606/
https://ncbi.nlm.nih.gov/pubmed/16922677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061085
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