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Selection and Optimization of Asymmetric siRNA Targeting the Human c-MET Gene
The silencing of specific oncogenes via RNA interference (RNAi) holds great promise for the future of cancer therapy. RNAi is commonly carried out using small interfering RNA (siRNA) composed of a 19 bp duplex region with a 2-nucleotide overhang at each 3’ end. This classical siRNA structure, howeve...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Korean Society for Molecular and Cellular Biology
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3887682/ https://ncbi.nlm.nih.gov/pubmed/22058018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-011-0160-1 |
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