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Selection and Optimization of Asymmetric siRNA Targeting the Human c-MET Gene

The silencing of specific oncogenes via RNA interference (RNAi) holds great promise for the future of cancer therapy. RNAi is commonly carried out using small interfering RNA (siRNA) composed of a 19 bp duplex region with a 2-nucleotide overhang at each 3’ end. This classical siRNA structure, howeve...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jo, Seul-gi, Hong, Sun Woo, Yoo, Jae Wook, Lee, Chang Han, Kim, Sera, Kim, Soyoun, Lee, Dong-ki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Korean Society for Molecular and Cellular Biology 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887682/
https://ncbi.nlm.nih.gov/pubmed/22058018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-011-0160-1
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