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Target Gene Abundance Contributes to the Efficiency of siRNA-Mediated Gene Silencing
The gene-silencing activity of a small interfering RNA (siRNA) is determined by various factors. Considering that RNA interference (RNAi) is an unparalleled technology in both basic research and therapeutic applications, thorough understanding of the factors determining RNAi activity is critical. Th...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4026300/ https://ncbi.nlm.nih.gov/pubmed/24527979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2013.0466 |
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