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Plk1-Targeted Small Molecule Inhibitors: Molecular Basis for Their Potency and Specificity

Members of polo-like kinases (collectively, Plks) have been identified in various eukaryotic organisms and play pivotal roles in cell proliferation. They are characterized by the presence of a distinct region of homology in the C-terminal noncatalytic domain, called polo-box domain (PBD). Among them...

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Bibliografski detalji
Glavni autori: N. Murugan, Ravichandran, Park, Jung-Eun, Kim, Eun-Hee, Shin, Song Yub, Cheong, Chaejoon, Lee, Kyung S, Bang, Jeong Kyu
Format: Artigo
Jezik:Inglês
Izdano: Korean Society for Molecular and Cellular Biology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887635/
https://ncbi.nlm.nih.gov/pubmed/21809214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-011-0126-3
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