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Plk1-Targeted Small Molecule Inhibitors: Molecular Basis for Their Potency and Specificity
Members of polo-like kinases (collectively, Plks) have been identified in various eukaryotic organisms and play pivotal roles in cell proliferation. They are characterized by the presence of a distinct region of homology in the C-terminal noncatalytic domain, called polo-box domain (PBD). Among them...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Korean Society for Molecular and Cellular Biology
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3887635/ https://ncbi.nlm.nih.gov/pubmed/21809214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-011-0126-3 |
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