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PARKIN ubiquitin ligase mediates resistance to intracellular pathogens
Ubiquitin-mediated targeting of intracellular bacteria to the autophagy pathway is a key innate defense mechanism against invading microbes, including the important human pathogen Mycobacterium tuberculosis. However, the ubiquitin ligases responsible for catalyzing ubiquitin chains that surround int...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3886920/ https://ncbi.nlm.nih.gov/pubmed/24005326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12566 |
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