PARKIN ubiquitin ligase mediates resistance to intracellular pathogens

Ubiquitin-mediated targeting of intracellular bacteria to the autophagy pathway is a key innate defense mechanism against invading microbes, including the important human pathogen Mycobacterium tuberculosis. However, the ubiquitin ligases responsible for catalyzing ubiquitin chains that surround int...

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Hlavní autoři: Manzanillo, Paolo S., Ayres, Janelle S., Watson, Robert O., Collins, Angela C., Souza, Gianne, Rae, Chris S., Schneider, David S., Nakamura, Ken, Shiloh, Michael U., Cox, Jeffery S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886920/
https://ncbi.nlm.nih.gov/pubmed/24005326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12566
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