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The polarization of immune cells in the tumour environment by TGFβ
Transforming growth factor-β (TGFβ) is an immunosuppressive cytokine produced by tumour cells and immune cells that can polarize many arms of the immune system. This Review covers the effects of TGFβ on NK cells, dendritic cells, macrophages, neutrophils, CD8(+) and CD4(+) effector and regulatory ce...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3885992/ https://ncbi.nlm.nih.gov/pubmed/20616810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri2808 |
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