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Truncated form of TGFβRII, but not its absence, induces memory CD8(+) T cell expansion and lymphoproliferative disorder in mice
Inflammatory and anti-inflammatory cytokines play an important role in the generation of effector and memory CD8(+) T cells. We used two different models, transgenic expression of truncated (dominant negative) form of TGF-β receptor II (dnTGFβRII) and Cre-mediated deletion of the floxed TGFβRII to e...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3690649/ https://ncbi.nlm.nih.gov/pubmed/23686479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300397 |
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