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Truncated form of TGFβRII, but not its absence, induces memory CD8(+) T cell expansion and lymphoproliferative disorder in mice

Inflammatory and anti-inflammatory cytokines play an important role in the generation of effector and memory CD8(+) T cells. We used two different models, transgenic expression of truncated (dominant negative) form of TGF-β receptor II (dnTGFβRII) and Cre-mediated deletion of the floxed TGFβRII to e...

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Detaylı Bibliyografya
Asıl Yazarlar: Ishigame, Harumichi, Mosaheb, Munir M., Sanjabi, Shomyseh, Flavell, Richard A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690649/
https://ncbi.nlm.nih.gov/pubmed/23686479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300397
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