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Opposing effects of TGF-β and IL-15 control the number of short-lived effector CD8(+) T cells
An effective immune response against infectious agents involves massive expansion of CD8(+) T cells. Once the infection is cleared, the majority of these effector cells die through unknown mechanisms, leaving behind only memory precursor cells. How is expansion controlled to maximize pathogen cleara...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2765785/ https://ncbi.nlm.nih.gov/pubmed/19604492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.04.020 |
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