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Lack of Sprouty 1 and 2 enhances survival of effector CD8(+) T cells and yields more protective memory cells
Identifying novel pathways that promote robust function and longevity of cytotoxic T cells has promising potential for immunotherapeutic strategies to combat cancer and chronic infections. We show that sprouty 1 and 2 (Spry1/2) molecules regulate the survival and function of memory CD8(+) T cells. S...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6156615/ https://ncbi.nlm.nih.gov/pubmed/30126987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808320115 |
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