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Memory CD4(+) T-cell–mediated protection depends on secondary effectors that are distinct from and superior to primary effectors

Whether differences between naive cell-derived primary (1°) and memory cell-derived secondary (2°) CD4(+) T-cell effectors contribute to protective recall responses is unclear. Here, we compare these effectors directly after influenza A virus infection. Both develop with similar kinetics, but 2° eff...

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Detalhes bibliográficos
Main Authors: Strutt, Tara M., McKinstry, K. Kai, Kuang, Yi, Bradley, Linda M., Swain, Susan L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458385/
https://ncbi.nlm.nih.gov/pubmed/22927425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205894109
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