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Short-lived Antigen Recognition but not Viral Infection at a Defined Checkpoint Programs Effector CD4 T Cells to become Protective Memory()
While memory CD4 T cells are critical for effective immunity to pathogens, the mechanisms underlying their generation are still poorly defined. We find that following murine influenza infection, most effector CD4 T cells undergo apoptosis unless they encounter cognate Ag at a defined stage near the...
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| Publicado no: | J Immunol |
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| Principais autores: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5113829/ https://ncbi.nlm.nih.gov/pubmed/27798159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600838 |
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