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Short-lived Antigen Recognition but not Viral Infection at a Defined Checkpoint Programs Effector CD4 T Cells to become Protective Memory()

While memory CD4 T cells are critical for effective immunity to pathogens, the mechanisms underlying their generation are still poorly defined. We find that following murine influenza infection, most effector CD4 T cells undergo apoptosis unless they encounter cognate Ag at a defined stage near the...

詳細記述

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書誌詳細
出版年:J Immunol
主要な著者: Bautista, Bianca L., Devarajan, Priyadharshini, McKinstry, K. Kai, Strutt, Tara M., Vong, Allen, Jones, Michael, Kuang, Yi, Mott, Daniel, Swain, Susan L.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113829/
https://ncbi.nlm.nih.gov/pubmed/27798159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600838
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